PDBsum entry 4lg6

Structural protein

PDB id: 4lg6

Contents

Protein chains

163 a.a.

13 a.a.

Ligands

UNX ×3

Waters ×53

PDB id:

4lg6

Name:

Structural protein

Title:

Crystal structure of ankra2-ccdc8 complex

Structure:

Ankyrin repeat family a protein 2. Chain: a. Synonym: rfxank-like protein 2. Engineered: yes. Coiled-coil domain-containing protein 8. Chain: b. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ankra2, ankra. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Other_details: synthetic peptide

Resolution:

1.80Å R-factor: 0.197 R-free: 0.209

Authors:

C.Xu,C.Bian,W.Tempel,F.Mackenzie,C.Bountra,C.H.Arrowsmith, A.M.Edwards,J.Min,Structural Genomics Consortium (Sgc)

Key ref:

J.Nie et al. (2015). Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8. Structure, 23, 700-712. PubMed id: 25752541 DOI: 10.1016/j.str.2015.02.001

Date:

27-Jun-13 Release date: 25-Sep-13

Protein chain

Q9H9E1  (ANRA2_HUMAN) -  Ankyrin repeat family A protein 2 from Homo sapiens

Seq: 313 a.a.

Struc: 163 a.a.

Protein chain

Q9H0W5  (CCDC8_HUMAN) -  Coiled-coil domain-containing protein 8 from Homo sapiens

Seq: 538 a.a.

Struc: 13 a.a.

DOI no: 10.1016/j.str.2015.02.001

Structure 23:700-712 (2015)

PubMed id: 25752541

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.

J.Nie, C.Xu, J.Jin, J.A.Aka, W.Tempel, V.Nguyen, L.You, R.Weist, J.Min, T.Pawson, X.J.Yang.

ABSTRACT

No abstract given.