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PDBsum entry 4kzw

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protein ligands metals Protein-protein interface(s) links
Carbohydrate-binding protein PDB id
4kzw

 

 

 

 

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Contents
Protein chains
133 a.a.
Ligands
FLC
Metals
_NA
_CA ×4
Waters ×154
PDB id:
4kzw
Name: Carbohydrate-binding protein
Title: Structure of the carbohydrate-recognition domain of thE C-type lectin mincle
Structure: C-type lectin mincle. Chain: a, b. Fragment: carbohydrate recognition domain (unp residues 79-208). Engineered: yes
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: clec4e. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.85Å     R-factor:   0.182     R-free:   0.227
Authors: H.Feinberg,S.A.F.Jegouzo,T.J.W.Rowntree,Y.Guan,M.A.Brash,M.E.Taylor, W.I.Weis,K.Drickamer
Key ref: H.Feinberg et al. (2013). Mechanism for recognition of an unusual mycobacterial glycolipid by the macrophage receptor mincle. J Biol Chem, 288, 28457-28465. PubMed id: 23960080 DOI: 10.1074/jbc.M113.497149
Date:
30-May-13     Release date:   28-Aug-13    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
E1BHM0  (E1BHM0_BOVIN) -  C-type lectin domain family 4 member E from Bos taurus
Seq:
Struc:
211 a.a.
133 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 

 
DOI no: 10.1074/jbc.M113.497149 J Biol Chem 288:28457-28465 (2013)
PubMed id: 23960080  
 
 
Mechanism for recognition of an unusual mycobacterial glycolipid by the macrophage receptor mincle.
H.Feinberg, S.A.Jégouzo, T.J.Rowntree, Y.Guan, M.A.Brash, M.E.Taylor, W.I.Weis, K.Drickamer.
 
  ABSTRACT  
 
No abstract given.

 

 

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