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PDBsum entry 4kga
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PDB id:
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Hydrolase
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Title:
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Crystal structure of kallikrein-related peptidase 4
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Structure:
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Kallikrein-4. Chain: a, b. Fragment: related peptidase 4, unp residues 31-253. Synonym: enamel matrix serine proteinase 1, kallikrein-like protein 1, klk-l1, prostase, serine protease 17. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: klk4. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.32Å
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R-factor:
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0.222
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R-free:
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0.264
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Authors:
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O.V.Ilyichova,J.E.Swedberg,S.J.De Veer,K.C.Sit,J.M.Harris,A.M.Buckle
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Key ref:
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B.T.Riley
et al.
(2016).
Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.
Sci Rep,
6,
35385.
PubMed id:
DOI:
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Date:
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29-Apr-13
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Release date:
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30-Apr-14
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PROCHECK
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Headers
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References
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Q9Y5K2
(KLK4_HUMAN) -
Kallikrein-4 from Homo sapiens
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Seq:
Struc:
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254 a.a.
221 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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DOI no:
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Sci Rep
6:35385
(2016)
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PubMed id:
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Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.
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B.T.Riley,
O.Ilyichova,
M.G.Costa,
B.T.Porebski,
S.J.de Veer,
J.E.Swedberg,
I.Kass,
J.M.Harris,
D.E.Hoke,
A.M.Buckle.
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ABSTRACT
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Links
