UniProt functional annotation for P10903

UniProt code: P10903.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Catalyzes nitrate uptake, nitrite uptake and nitrite export across the cytoplasmic membrane. Functions as a nitrate/nitrite exchanger, and protons are probably not co-transported with the substrate. {ECO:0000269|PubMed:11967075, ECO:0000269|PubMed:15667293, ECO:0000269|PubMed:16804183, ECO:0000269|PubMed:23665960, ECO:0000269|PubMed:2668029}.
 
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000269|PubMed:15919996}.
Induction: Highly expressed during anaerobic growth in the presence of nitrate. {ECO:0000269|PubMed:16804183, ECO:0000269|PubMed:2668029}.
Similarity: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.