PDBsum entry 4jjc

Transferase

PDB id: 4jjc

Contents

Protein chain

58 a.a.

Ligands

PEG

Waters ×76

PDB id:

4jjc

Name:

Transferase

Title:

Crystal structure of the abl-sh3 domain at ph5

Structure:

Tyrosine-protein kinase abl1. Chain: a. Fragment: sh3 domain, unp residues 60-121. Synonym: proto-oncogene tyrosine-protein kinase abl1, abelson murine leukemia viral oncogene homolog 1, abelson tyrosine-protein kinase 1, proto-oncogenE C-abl, p150. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: abl, abl1, jtk7. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.60Å R-factor: 0.176 R-free: 0.219

Authors:

A.Camara-Artigas,J.M.Martin-Garcia

Key ref:

A.Camara-Artigas and j.m.martin-garcia Crystal structure of the abl-Sh3 domain at ph5. To be published, .

Date:

07-Mar-13 Release date: 12-Mar-14

Protein chain

P00519  (ABL1_HUMAN) -  Tyrosine-protein kinase ABL1 from Homo sapiens

Seq: 1130 a.a.

Struc: 58 a.a.

Enzyme reactions

• Enzyme class: E.C.2.7.10.2 - non-specific protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site