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PDBsum entry 4j6k

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protein ligands Protein-protein interface(s) links
Immune system PDB id
4j6k

 

 

 

 

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Contents
Protein chains
127 a.a.
120 a.a.
133 a.a.
124 a.a.
Ligands
SO4 ×4
Waters ×127
PDB id:
4j6k
Name: Immune system
Title: Crystal structure of calcium2+-free wild-type cd23 lectin domain (crystal form b)
Structure: Low affinity immunoglobulin epsilon fc receptor. Chain: a, b, c, d, e, f, g, h. Fragment: soluble head domain of the b-cell receptor cd23 (unp residues 156-298). Synonym: blast-2, c-type lectin domain family 4 member j, fc-epsilon- rii, immunoglobulin e-binding factor, lymphocyte ige receptor, low affinity immunoglobulin epsilon fc receptor membrane-bound form, low affinity immunoglobulin epsilon fc receptor soluble form. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cd23a, clec4j, fce2, fcer2, igebf. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.30Å     R-factor:   0.193     R-free:   0.218
Authors: B.Dhaliwal,M.O.Y.Pang,B.J.Sutton
Key ref: B.Dhaliwal et al. (2013). Conformational plasticity at the IgE-binding site of the B-cell receptor CD23. Mol Immunol, 56, 693-697. PubMed id: 23933509 DOI: 10.1016/j.molimm.2013.07.005
Date:
11-Feb-13     Release date:   28-Aug-13    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P06734  (FCER2_HUMAN) -  Low affinity immunoglobulin epsilon Fc receptor from Homo sapiens
Seq:
Struc:
321 a.a.
127 a.a.
Protein chain
Pfam   ArchSchema ?
P06734  (FCER2_HUMAN) -  Low affinity immunoglobulin epsilon Fc receptor from Homo sapiens
Seq:
Struc:
321 a.a.
120 a.a.
Protein chains
Pfam   ArchSchema ?
P06734  (FCER2_HUMAN) -  Low affinity immunoglobulin epsilon Fc receptor from Homo sapiens
Seq:
Struc:
321 a.a.
133 a.a.
Protein chain
Pfam   ArchSchema ?
P06734  (FCER2_HUMAN) -  Low affinity immunoglobulin epsilon Fc receptor from Homo sapiens
Seq:
Struc:
321 a.a.
124 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
DOI no: 10.1016/j.molimm.2013.07.005 Mol Immunol 56:693-697 (2013)
PubMed id: 23933509  
 
 
Conformational plasticity at the IgE-binding site of the B-cell receptor CD23.
B.Dhaliwal, M.O.Pang, D.Yuan, N.Yahya, S.M.Fabiane, J.M.McDonnell, H.J.Gould, A.J.Beavil, B.J.Sutton.
 
  ABSTRACT  
 
No abstract given.

 

 

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