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UniProt functional annotation for O43752 | ||
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| UniProt code: O43752. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Involved in intracellular vesicle trafficking. |
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| Subunit: | |
Identified in a complex containing STX6, STX12, VAMP4 and VTI1A (PubMed:17159904). Binds EEA1 (By similarity). Interacts with VPS45A (By similarity). Interacts with MARCHF2 and MARCHF3 (By similarity). Interacts with GOPC (PubMed:11384996). Interacts with UHRF1BP1L (via C-terminal coiled-coil domain) (PubMed:20163565). Interacts with BAIAP3; this interaction is increased in the presence of calcium (PubMed:28626000). {ECO:0000250|UniProtKB:Q63635, ECO:0000250|UniProtKB:Q9JKK1, ECO:0000269|PubMed:11384996, ECO:0000269|PubMed:17159904, ECO:0000269|PubMed:20163565, ECO:0000269|PubMed:28626000}. |
| Subcellular location: | |
Golgi apparatus membrane {ECO:0000305}; Single- pass type IV membrane protein {ECO:0000305}. |
| Similarity: | |
Belongs to the syntaxin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.