PDBsum entry 4ixd

Immune system

PDB id: 4ixd

Contents

Protein chain

182 a.a.

Ligands

1HV

Metals

_MG

Waters ×299

PDB id:

4ixd

Name:

Immune system

Title:

X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution

Structure:

Integrin alpha-l. Chain: a. Fragment: i-domain, unp residues 152-336. Synonym: cd11 antigen-like family member a, leukocyte adhesion glycoprotein lfa-1 alpha chain, lfa-1a, leukocyte function-associated molecule 1 alpha chain. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: itgal, cd11a. Expressed in: escherichia coli. Expression_system_taxid: 511693.

Resolution:

1.80Å R-factor: 0.173 R-free: 0.199

Authors:

J.Kallen

Key ref:

M.Hintersteiner et al. Identification and X-Ray structure based investigatio icam-1 binding enhancing small molecule activator of. To be published, .

Date:

25-Jan-13 Release date: 29-Jan-14

Protein chain

P20701  (ITAL_HUMAN) -  Integrin alpha-L from Homo sapiens

Seq: 1170 a.a.

Struc: 182 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)