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PDBsum entry 4i6j

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protein Protein-protein interface(s) links
Transcription PDB id
4i6j

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
503 a.a.
394 a.a.
130 a.a.
Waters ×156
PDB id:
4i6j
Name: Transcription
Title: A ubiquitin ligase-substrate complex
Structure: Cryptochrome-2. Chain: a. Fragment: unp residues 1-544. Engineered: yes. F-box/lrr-repeat protein 3. Chain: b. Synonym: f-box and leucine-rich repeat protein 3a, f-box/lrr-repeat protein 3a. Engineered: yes.
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cry2, kiaa0658. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Homo sapiens. Human. Organism_taxid: 9606.
Resolution:
2.70Å     R-factor:   0.206     R-free:   0.265
Authors: W.Xing,L.Busino,T.R.Hinds,S.T.Marionni,N.H.Saifee,M.F.Bush,M.Pagano, N.Zheng
Key ref: W.Xing et al. (2013). SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature, 496, 64-68. PubMed id: 23503662 DOI: 10.1038/nature11964
Date:
29-Nov-12     Release date:   13-Mar-13    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9R194  (CRY2_MOUSE) -  Cryptochrome-2 from Mus musculus
Seq:
Struc:
 
Seq:
Struc:
592 a.a.
503 a.a.
Protein chain
Pfam   ArchSchema ?
Q9UKT7  (FBXL3_HUMAN) -  F-box/LRR-repeat protein 3 from Homo sapiens
Seq:
Struc:
428 a.a.
394 a.a.
Protein chain
Pfam   ArchSchema ?
P63208  (SKP1_HUMAN) -  S-phase kinase-associated protein 1 from Homo sapiens
Seq:
Struc:
163 a.a.
130 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
DOI no: 10.1038/nature11964 Nature 496:64-68 (2013)
PubMed id: 23503662  
 
 
SCF(FBXL3) ubiquitin ligase targets cryptochromes at their cofactor pocket.
W.Xing, L.Busino, T.R.Hinds, S.T.Marionni, N.H.Saifee, M.F.Bush, M.Pagano, N.Zheng.
 
  ABSTRACT  
 
No abstract given.

 

 

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