PDBsum entry 4hwu

Immune system

PDB id: 4hwu

Contents

Protein chains

81 a.a.

73 a.a.

Waters ×16

PDB id:

4hwu

Name:

Immune system

Title:

Crystal structure of the ig-c2 type 1 domain from mouse fibroblast growth factor receptor 2 (fgfr2) [nysgrc-005912]

Structure:

Fibroblast growth factor receptor 2. Chain: a, b. Fragment: unp residues 45-127. Synonym: fgfr-2, keratinocyte growth factor receptor, kgfr. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: bek, ect1, fgfr2. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.

Resolution:

2.90Å R-factor: 0.228 R-free: 0.252

Authors:

P.R.Kumar,M.Ahmed,R.Banu,R.Bhosle,D.Calarese,A.Celikigil,S.Chamala, M.K.Chan,S.Chowdhury,A.Fiser,S.Garforth,A.S.Glenn,B.Hillerich, K.Khafizov,J.Love,H.Patel,R.Rubinstein,R.Seidel,M.Stead,R.Toro, S.G.Nathenson,S.C.Almo,New York Structural Genomics Research Consortium (Nysgrc),Atoms-To-Animals: The Immune Function Network (Ifn)

Key ref:

P.R.Kumar et al. Crystal structure of the ig-C2 type 1 domain from mou fgfr2 [nysgrc-005912]. To be published, .

Date:

08-Nov-12 Release date: 21-Nov-12

Protein chain

P21803  (FGFR2_MOUSE) -  Fibroblast growth factor receptor 2 from Mus musculus

Seq: 821 a.a.

Struc: 81 a.a.

Protein chain

P21803  (FGFR2_MOUSE) -  Fibroblast growth factor receptor 2 from Mus musculus

Seq: 821 a.a.

Struc: 73 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.2.7.10.1 - receptor protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site