PDBsum entry 4hk2

Signaling protein/inhibitor

PDB id: 4hk2

Contents

Protein chains

74 a.a.

Ligands

SO4

Waters ×245

PDB id:

4hk2

Name:

Signaling protein/inhibitor

Title:

U7ub25.2540

Structure:

Ubiquitin. Chain: a, b, c, d. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc, ubiquitin. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.40Å R-factor: 0.199 R-free: 0.236

Authors:

J.M.Murray,L.Rouge

Key ref:

Y.Zhang et al. Potent and selective inhibitors of usp7/hausp activit protein conformational stabilization. To be published, .

Date:

14-Oct-12 Release date: 21-Nov-12

Protein chains

P0CG48  (UBC_HUMAN) -  Polyubiquitin-C from Homo sapiens

Seq: 685 a.a.

Struc: 74 a.a.*

* PDB and UniProt seqs differ at 10 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?