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PDBsum entry 4gz8
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Signaling protein
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PDB id
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4gz8
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PDB id:
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| Name: |
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Signaling protein
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Title:
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Mouse semaphorin 3a, domains sema-psi-ig
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Structure:
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Semaphorin-3a. Chain: a, b. Fragment: unp residues 21-675. Synonym: semaphorin iii, sema iii, semaphorin-d, sema d. Engineered: yes
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Source:
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Mus musculus. Mouse. Organism_taxid: 10090. Gene: sema3a, semad, semd. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293
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Resolution:
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3.30Å
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R-factor:
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0.216
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R-free:
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0.265
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Authors:
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B.J.C.Janssen,T.Malinauskas,C.Siebold,E.Y.Jones
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Key ref:
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B.J.Janssen
et al.
(2012).
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
Nat Struct Biol,
19,
1293-1299.
PubMed id:
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Date:
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06-Sep-12
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Release date:
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17-Oct-12
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PROCHECK
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Headers
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References
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O08665
(SEM3A_MOUSE) -
Semaphorin-3A from Mus musculus
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Seq:
Struc:
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772 a.a.
557 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 28 residue positions (black
crosses)
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Nat Struct Biol
19:1293-1299
(2012)
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PubMed id:
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Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
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B.J.Janssen,
T.Malinauskas,
G.A.Weir,
M.Z.Cader,
C.Siebold,
E.Y.Jones.
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ABSTRACT
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Links
