| UniProt functional annotation for O43070 | |||
| UniProt code: O43070. |
| Organism: | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Taxonomy: | Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. | |
| Function: | Required for DNA damage repair and S-phase DNA damage checkpoint. Involved in telomere length maintenance and maintenance of chromatin structure. {ECO:0000269|PubMed:12944481, ECO:0000269|PubMed:12944482}. | |
| Subunit: | Associates with rad32. Forms a multisubunit endonuclease complex, MRN, together with rad32 and rad50. {ECO:0000269|PubMed:12944482}. | |
| Subcellular location: | Nucleus {ECO:0000269|PubMed:12944481}. Chromosome, telomere {ECO:0000269|PubMed:12944481, ECO:0000269|PubMed:12944482}. | |
Annotations taken from UniProtKB at the EBI.