UniProt functional annotation for O43070

UniProt code: O43070.

Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
 
Function: Required for DNA damage repair and S-phase DNA damage checkpoint. Involved in telomere length maintenance and maintenance of chromatin structure. {ECO:0000269|PubMed:12944481, ECO:0000269|PubMed:12944482}.
 
Subunit: Associates with rad32. Forms a multisubunit endonuclease complex, MRN, together with rad32 and rad50. {ECO:0000269|PubMed:12944482}.
Subcellular location: Nucleus {ECO:0000269|PubMed:12944481}. Chromosome, telomere {ECO:0000269|PubMed:12944481, ECO:0000269|PubMed:12944482}.

Annotations taken from UniProtKB at the EBI.