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UniProt functional annotation for O00478 | ||
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| UniProt code: O00478. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Plays a role in T-cell responses in the adaptive immune response. {ECO:0000269|PubMed:22767497}. |
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| Subunit: | |
Homodimer. {ECO:0000269|PubMed:22846996}. |
| Subcellular location: | |
Cell membrane {ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:22767497}; Single-pass type I membrane protein {ECO:0000269|PubMed:21918970, ECO:0000269|PubMed:22767497}. |
| Tissue specificity: | |
Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes. {ECO:0000269|PubMed:20610803}. |
| Ptm: | |
N-glycosylated. {ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:20610803}. |
| Similarity: | |
Belongs to the immunoglobulin superfamily. BTN/MOG family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.