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PDBsum entry 4f7z
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PDB id:
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Exocytosis
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Title:
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Conformational dynamics of exchange protein directly activated by camp
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Structure:
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Rap guanine nucleotide exchange factor 4. Chain: a. Fragment: see remark 999. Synonym: epac2, exchange factor directly activated by camp 2, exchange protein directly activated by camp 2, epac 2, camp-dependent rap1 guanine-nucleotide exchange factor, camp-regulated guanine nucleotide exchange factor ii, camp-gefii. Engineered: yes. Mutation: yes
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Source:
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Mus musculus. Mouse. Organism_taxid: 10090. Gene: rapgef4, cgef2, epac2. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.60Å
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R-factor:
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0.222
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R-free:
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0.282
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Authors:
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M.A.White,T.N.Tsalkova,F.C.Mei,T.Liu,V.L.Woods,X.Cheng
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Key ref:
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M.A.White
et al.
(2012).
Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP.
Plos One,
7,
e49932.
PubMed id:
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Date:
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16-May-12
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Release date:
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03-Oct-12
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PROCHECK
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Headers
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References
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Q9EQZ6
(RPGF4_MOUSE) -
Rap guanine nucleotide exchange factor 4 from Mus musculus
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Seq:
Struc:
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1011 a.a.
946 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Plos One
7:e49932
(2012)
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PubMed id:
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Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP.
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M.A.White,
S.Li,
T.Tsalkova,
F.C.Mei,
T.Liu,
V.L.Woods,
X.Cheng.
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ABSTRACT
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Links
