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UniProt functional annotation for P34712 | ||
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| UniProt code: P34712. |
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| Organism: | |
Caenorhabditis elegans. |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. |
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| Function: | |
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. |
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| Catalytic activity: | |
Reaction=ATP + H(2)O + xenobiotic(Side 1) = ADP + phosphate + xenobiotic(Side 2).; EC=7.6.2.2; |
| Subcellular location: | |
Membrane; Multi-pass membrane protein. |
| Tissue specificity: | |
Intestinal cells. {ECO:0000269|PubMed:8096815}. |
| Similarity: | |
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.