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PDBsum entry 4f2q
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Transport protein/agonist
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PDB id
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4f2q
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PDB id:
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| Name: |
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Transport protein/agonist
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Title:
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Quisqualate bound to the d655a mutant of the ligand binding domain of glua3
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Structure:
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Glutamate receptor 3. Chain: a. Synonym: glur-3, ampa-selective glutamate receptor 3, glur-c, glur- k3, glutamate receptor ionotropic, ampa 3, glua3. Engineered: yes. Mutation: yes
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Source:
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Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: glur3, gria3, gria3. Glua3. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.20Å
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R-factor:
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0.201
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R-free:
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0.261
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Authors:
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A.H.Ahmed,R.E.Oswald
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Key ref:
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S.M.Holley
et al.
(2012).
The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry,
51,
4015-4027.
PubMed id:
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Date:
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08-May-12
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Release date:
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30-May-12
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PROCHECK
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Headers
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References
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P19492
(GRIA3_RAT) -
Glutamate receptor 3 from Rattus norvegicus
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Seq:
Struc:
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888 a.a.
258 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 3 residue positions (black
crosses)
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Biochemistry
51:4015-4027
(2012)
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PubMed id:
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The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
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S.M.Holley,
A.H.Ahmed,
J.Srinivasan,
S.E.Murthy,
G.A.Weiland,
R.E.Oswald,
L.M.Nowak.
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ABSTRACT
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Links
