 |
PDBsum entry 4f1y
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Transport protein/agonist
|
PDB id
|
|
|
|
4f1y
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Transport protein/agonist
|
|
|
Title:
|
|
Cnqx bound to the ligand binding domain of glua3
|
|
Structure:
|
|
Glutamate receptor 3. Chain: a, c. Synonym: glur-3, ampa-selective glutamate receptor 3, glur-c, glur- k3, glutamate receptor ionotropic, ampa 3, glua3. Engineered: yes
|
|
Source:
|
|
Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: glur3, gria3, gria3. Glua3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
Resolution:
|
|
|
1.79Å
|
R-factor:
|
0.208
|
R-free:
|
0.251
|
|
|
Authors:
|
|
A.H.Ahmed,R.E.Oswald
|
|
Key ref:
|
|
S.M.Holley
et al.
(2012).
The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
Biochemistry,
51,
4015-4027.
PubMed id:
|
|
|
Date:
|
|
|
07-May-12
|
Release date:
|
16-May-12
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
P19492
(GRIA3_RAT) -
Glutamate receptor 3 from Rattus norvegicus
|
|
|
|
Seq:
Struc:
|
|
|
|
888 a.a.
258 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
| |
|
|
Biochemistry
51:4015-4027
(2012)
|
|
PubMed id:
|
|
|
|
|
|
| |
|
The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activation.
|
|
S.M.Holley,
A.H.Ahmed,
J.Srinivasan,
S.E.Murthy,
G.A.Weiland,
R.E.Oswald,
L.M.Nowak.
|
|
|
|
|
| |
ABSTRACT
|
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
 |
 |
|
Links
