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PDBsum entry 4f09
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Transferase/transferase inhibitor
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PDB id
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4f09
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References listed in PDB file
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Key reference
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Title
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Discovery and optimization of c-2 methyl imidazopyrrolopyridines as potent and orally bioavailable jak1 inhibitors with selectivity over jak2.
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Authors
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M.Zak,
R.Mendonca,
M.Balazs,
K.Barrett,
P.Bergeron,
W.S.Blair,
C.Chang,
G.Deshmukh,
J.Devoss,
P.S.Dragovich,
C.Eigenbrot,
N.Ghilardi,
P.Gibbons,
S.Gradl,
C.Hamman,
E.J.Hanan,
E.Harstad,
P.R.Hewitt,
C.A.Hurley,
T.Jin,
A.Johnson,
T.Johnson,
J.R.Kenny,
M.F.Koehler,
P.Bir kohli,
J.J.Kulagowski,
S.Labadie,
J.Liao,
M.Liimatta,
Z.Lin,
P.J.Lupardus,
R.J.Maxey,
J.M.Murray,
R.Pulk,
M.Rodriguez,
S.Savage,
S.Shia,
M.Steffek,
S.Ubhayakar,
M.Ultsch,
A.Van abbema,
S.I.Ward,
L.Xiao,
Y.Xiao.
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Ref.
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J Med Chem, 2012,
55,
6176-6193.
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PubMed id
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Abstract
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No abstract given.
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