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PDBsum entry 4ek6

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protein ligands links
Transferase/transferase inhibitor PDB id
4ek6
Jmol PyMol
Contents
Protein chain
279 a.a.
Ligands
10K
Waters ×237
PDB id:
4ek6
Name: Transferase/transferase inhibitor
Title: Crystal structure of the cdk2 in complex with aminopyrazole
Structure: Cyclin-dependent kinase 2. Chain: a. Synonym: cell division protein kinase 2, p33 protein kinase engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdk2, cdkn2. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high-five.
Resolution:
1.52Å     R-factor:   0.189     R-free:   0.217
Authors: Y.N.Kang,J.A.Stuckey
Key ref: Y.N.Kang and j.a.stuckey Tba. To be published, .
Date:
09-Apr-12     Release date:   01-May-13    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P24941  (CDK2_HUMAN) -  Cyclin-dependent kinase 2
Seq:
Struc:
298 a.a.
278 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.11.22  - Cyclin-dependent kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a protein = ADP + a phosphoprotein
ATP
+ protein
= ADP
+ phosphoprotein
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cyclin A1-CDK2 complex   19 terms 
  Biological process     regulation of gene silencing   32 terms 
  Biochemical function     nucleotide binding     13 terms  

 

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