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PDBsum entry 4e35
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Protein transport/protein binding
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PDB id
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4e35
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PDB id:
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| Name: |
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Protein transport/protein binding
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Title:
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Crystal structure of cftr associated ligand (cal) pdz domain bound to ical36-l (ansrwptsil) peptide
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Structure:
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Golgi-associated pdz and coiled-coil motif-containing protein. Chain: a, b. Fragment: pdz domain (unp residues 284-370). Synonym: cal, cftr-associated ligand, fused in glioblastoma, pdz protein interacting specifically with tc10, pist. Engineered: yes. Ical50 peptide. Chain: c, d.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: gopc, cal, fig. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes
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Resolution:
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1.40Å
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R-factor:
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0.185
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R-free:
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0.198
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Authors:
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J.F.Amacher,D.R.Madden
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Key ref:
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J.F.Amacher
et al.
(2013).
Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop.
J Biol Chem,
288,
5114-5126.
PubMed id:
DOI:
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Date:
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09-Mar-12
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Release date:
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26-Dec-12
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PROCHECK
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Headers
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References
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Q9HD26
(GOPC_HUMAN) -
Golgi-associated PDZ and coiled-coil motif-containing protein from Homo sapiens
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Seq:
Struc:
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462 a.a.
87 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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DOI no:
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J Biol Chem
288:5114-5126
(2013)
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PubMed id:
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Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop.
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J.F.Amacher,
P.R.Cushing,
C.D.Bahl,
T.Beck,
D.R.Madden.
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ABSTRACT
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Links
