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PDBsum entry 4dzb
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protein Protein-protein interface(s) links
Immune system PDB id
4dzb

 

 

 

 

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Contents
Protein chains
196 a.a.
244 a.a.
Waters ×271
PDB id:
4dzb
Name: Immune system
Title: Mucosal-associated invariant t cell receptor, valpha7.2jalpha33-vbeta2
Structure: Valpha7.2-jalpha33 (mait t cell receptor). Chain: a. Synonym: mucosal-associated invariant t cell receptor. Engineered: yes. Vbeta2 (mait t cell receptor). Chain: b. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.70Å     R-factor:   0.193     R-free:   0.231
Authors: O.Patel,J.Rossjohn
Key ref: R.Reantragoon et al. (2012). Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor. J Exp Med, 209, 761-774. PubMed id: 22412157
Date:
01-Mar-12     Release date:   28-Mar-12    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 196 a.a.
Protein chain
No UniProt id for this chain
Struc: 244 a.a.
Key:    Secondary structure  CATH domain

 

 
J Exp Med 209:761-774 (2012)
PubMed id: 22412157  
 
 
Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor.
R.Reantragoon, L.Kjer-Nielsen, O.Patel, Z.Chen, P.T.Illing, M.Bhati, L.Kostenko, M.Bharadwaj, B.Meehan, T.H.Hansen, D.I.Godfrey, J.Rossjohn, J.McCluskey.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23154222 J.Rossjohn, D.G.Pellicci, O.Patel, L.Gapin, and D.I.Godfrey (2012).
Recognition of CD1d-restricted antigens by natural killer T cells.
  Nat Rev Immunol, 12, 845-857.  
23051753 L.Kjer-Nielsen, O.Patel, A.J.Corbett, J.Le Nours, B.Meehan, L.Liu, M.Bhati, Z.Chen, L.Kostenko, R.Reantragoon, N.A.Williamson, A.W.Purcell, N.L.Dudek, M.J.McConville, R.A.O'Hair, G.N.Khairallah, D.I.Godfrey, D.P.Fairlie, J.Rossjohn, and J.McCluskey (2012).
MR1 presents microbial vitamin B metabolites to MAIT cells.
  Nature, 491, 717-723.
PDB code: 4gup
23178389 M.C.Gold, and D.M.Lewinsohn (2012).
Co-dependents: MR1-restricted MAIT cells and their antimicrobial function.
  Nat Rev Microbiol, 11, 14-19.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

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