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UniProt functional annotation for Q9UHF4 | ||
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| UniProt code: Q9UHF4. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. |
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| Subunit: | |
Heterodimer with IL20RB and heterodimer with IL10RB. {ECO:0000269|PubMed:11163236, ECO:0000269|PubMed:12351624, ECO:0000269|PubMed:14580208, ECO:0000269|PubMed:14764663, ECO:0000269|PubMed:22802649}. |
| Subcellular location: | |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Tissue specificity: | |
Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin. {ECO:0000269|PubMed:11163236, ECO:0000269|PubMed:14764663}. |
| Similarity: | |
Belongs to the type II cytokine receptor family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.