UniProt functional annotation for Q6UXL0

UniProt code: Q6UXL0.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
 
Subunit: Heterodimer with IL20RA and heterodimer with IL22RA1. {ECO:0000269|PubMed:11163236, ECO:0000269|PubMed:11564763, ECO:0000269|PubMed:12351624, ECO:0000269|PubMed:14580208, ECO:0000269|PubMed:22802649}.
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue specificity: Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. {ECO:0000269|PubMed:11163236}.
Similarity: Belongs to the type II cytokine receptor family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.