PDBsum entry 4dmu

Structural protein/protein binding

PDB id: 4dmu

Contents

Protein chains

(+ 0 more) 79 a.a.

(+ 0 more) 188 a.a.

Ligands

SO4 ×4

PDB id:

4dmu

Name:

Structural protein/protein binding

Title:

Crystal structure of the von willebrand factor a3 domain in complex with a collagen iii derived triple-helical peptide

Structure:

Collagen iii derived triple-helical peptide. Chain: a, c, e, g, i, k. Engineered: yes. Von willebrand factor. Chain: b, d, f, h, j, l. Synonym: vwf, von willebrand antigen 2, von willebrand antigen ii. Engineered: yes

Source:

Synthetic: yes. Other_details: synthetic peptide covers part of human collagen iii sequence. Homo sapiens. Human. Organism_taxid: 9606. Gene: vwf, f8vwf. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.80Å R-factor: 0.204 R-free: 0.253

Authors:

T.H.C.Brondijk,E.G.Huizinga

Key ref:

T.H.Brondijk et al. (2012). Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex. Proc Natl Acad Sci U S A, 109, 5253-5258. PubMed id: 22440751

Date:

08-Feb-12 Release date: 28-Mar-12

Protein chains

No UniProt id for this chain

Struc: 79 a.a.

Protein chains

P04275  (VWF_HUMAN) -  von Willebrand factor from Homo sapiens

Seq: 2813 a.a.

Struc: 188 a.a.

Proc Natl Acad Sci U S A 109:5253-5258 (2012)

PubMed id: 22440751

Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex.

T.H.Brondijk, D.Bihan, R.W.Farndale, E.G.Huizinga.

ABSTRACT

No abstract given.