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PDBsum entry 4dlq
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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
4dlq

 

 

 

 

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Contents
Protein chains
353 a.a.
15 a.a.
Ligands
NAG-NAG
NAG ×4
SO4 ×8
GOL ×2
Waters ×275
PDB id:
4dlq
Name: Signaling protein
Title: Crystal structure of the gain and hormr domains of cirl 1/latrophilin 1 (cl1)
Structure: Latrophilin-1. Chain: a. Fragment: gain and hormr domains of cl1, unp residues 460-837. Synonym: calcium-independent alpha-latrotoxin receptor 1, cirl-1. Engineered: yes. Latrophilin-1. Chain: b. Fragment: unp residues 838-850. Synonym: calcium-independent alpha-latrotoxin receptor 1, cirl-1.
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: lphn1, cirl, cirl1, cl1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_taxid: 7111
Resolution:
1.85Å     R-factor:   0.165     R-free:   0.185
Authors: D.Arac,A.A.Boucard,M.F.Bolliger,J.Nguyen,M.Soltis,T.C.Sudhof, A.T.Brunger
Key ref: D.Araç et al. (2012). A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. Embo J, 31, 1364-1378. PubMed id: 22333914
Date:
06-Feb-12     Release date:   22-Feb-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
O88917  (AGRL1_RAT) -  Adhesion G protein-coupled receptor L1 from Rattus norvegicus
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		1515 a.a.
353 a.a.
Protein chain
Pfam   ArchSchema ?
O88917  (AGRL1_RAT) -  Adhesion G protein-coupled receptor L1 from Rattus norvegicus
Seq:
Struc: 		 
Seq:
Struc: 		 
Seq:
Struc: 		1515 a.a.
15 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 

 
Embo J 31:1364-1378 (2012)
PubMed id: 22333914  
 
 
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.
D.Araç, A.A.Boucard, M.F.Bolliger, J.Nguyen, S.M.Soltis, T.C.Südhof, A.T.Brunger.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23407534 A.J.Venkatakrishnan, X.Deupi, G.Lebon, C.G.Tate, G.F.Schertler, and M.M.Babu (2013).
Molecular signatures of G-protein-coupled receptors.
  Nature, 494, 185-194.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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