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PDBsum entry 4djn

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
4djn
Jmol PyMol
Contents
Protein chains
287 a.a.
Ligands
SO4
EDO ×2
Waters ×122
PDB id:
4djn
Name: Oxidoreductase
Title: Crystal structure of a ribonucleotide reductase m2 b (rnrr2) sapiens at 2.20 a resolution
Structure: Ribonucleoside-diphosphate reductase subunit m2 b chain: a, b. Synonym: tp53-inducible ribonucleotide reductase m2 b, p53- ribonucleotide reductase small subunit 2-like protein, p53r engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rrm2b, p53r2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.20Å     R-factor:   0.195     R-free:   0.219
Authors: Joint Center For Structural Genomics (Jcsg),Partnership For Biology (Tcell)
Key ref: Joint center for structural genomics (jcsg) and partnership for t-cell biology Crystal structure of a ribonucleotide reductase m2 b from homo sapiens at 2.20 a resolution. To be published, .
Date:
02-Feb-12     Release date:   09-May-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q7LG56  (RIR2B_HUMAN) -  Ribonucleoside-diphosphate reductase subunit M2 B
Seq:
Struc:
351 a.a.
287 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.17.4.1  - Ribonucleoside-diphosphate reductase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin
2'-deoxyribonucleoside diphosphate
+ thioredoxin disulfide
+ H(2)O
= ribonucleoside diphosphate
+ thioredoxin
      Cofactor: Fe cation


Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     oxidation-reduction process   2 terms 
  Biochemical function     oxidoreductase activity     1 term  

 

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