PDBsum entry 4dbq

Motor protein, calcium binding protein

PDB id: 4dbq

Contents

Protein chains

744 a.a.

148 a.a.

Ligands

ADP-BEF

SO4 ×3

Metals

_MG

_CA ×4

Waters ×392

PDB id:

4dbq

Name:

Motor protein, calcium binding protein

Title:

Myosin vi d179y (md-insert2-cam, delta-insert1) post-rigor state

Structure:

Myosin-vi. Chain: a. Fragment: motor domain-insert2, unp f1rqi7 residues 2-277, 304-815. Engineered: yes. Mutation: yes. Calmodulin. Chain: b. Synonym: cam. Engineered: yes

Source:

Sus scrofa. Pigs,swine,wild boar. Organism_taxid: 9823. Gene: myo6. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Drosophila melanogaster. Fruit fly. Organism_taxid: 7227.

Resolution:

2.60Å R-factor: 0.172 R-free: 0.224

Authors:

O.Pylypenko,H.L.Sweeney,A.Houdusse

Key ref:

L.Song et al. Mutations in myosin VI that cause a loss of coordinat between heads provide insights into the structural ch underlying force generation and the importance of gat. To be published, .

Date:

16-Jan-12 Release date: 30-Jan-13

Protein chain

Q29122  (MYO6_PIG) -  Unconventional myosin-VI from Sus scrofa

Seq: 1254 a.a.

Struc: 744 a.a.*

Protein chain

P62152  (CALM_DROME) -  Calmodulin from Drosophila melanogaster

Seq: 149 a.a.

Struc: 148 a.a.

* PDB and UniProt seqs differ at 7 residue positions (black crosses)