PDBsum entry 4dbb

Protein transport

PDB id: 4dbb

Contents

Protein chain

150 a.a.

Ligands

ACY ×2

IPA ×2

GOL ×2

Metals

_CL

Waters ×78

PDB id:

4dbb

Name:

Protein transport

Title:

The ptb domain of mint1 is autoinhibited by a helix in thE C-terminal linker region

Structure:

Amyloid beta a4 precursor protein-binding family a member 1. Chain: a. Fragment: ptb domain, unp residues 453-643 with deletion of residues 497-508. Synonym: adapter protein x11alpha,neuron-specific x11 protein, neuronal munc18-1-interacting protein 1,mint-1,adapter protein x11alpha,neuron-specific x11 protein,neuronal munc18-1-interacting protein 1,mint-1.

Source:

Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: apba1, mint1, x11. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.90Å R-factor: 0.198 R-free: 0.225

Authors:

D.R.Tomchick,J.Rizo,A.Ho,Y.Xu

Key ref:

M.F.Matos et al. (2012). Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing. Proc Natl Acad Sci U S A, 109, 3802-3807. PubMed id: 22355143

Date:

13-Jan-12 Release date: 07-Mar-12

Protein chain

O35430  (APBA1_RAT) -  Amyloid-beta A4 precursor protein-binding family A member 1 from Rattus norvegicus

Seq: 839 a.a.

Struc: 150 a.a.

Proc Natl Acad Sci U S A 109:3802-3807 (2012)

PubMed id: 22355143

Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing.

M.F.Matos, Y.Xu, I.Dulubova, Z.Otwinowski, J.M.Richardson, D.R.Tomchick, J.Rizo, A.Ho.

ABSTRACT

No abstract given.