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PDBsum entry 4d9l
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protein Protein-protein interface(s) links
Immune system PDB id
4d9l

 

 

 

 

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Contents
Protein chains
214 a.a.
222 a.a.
Waters ×603
PDB id:
4d9l
Name: Immune system
Title: Fab structure of anti-HIV-1 gp120 v2 mab 697
Structure: Light chain of fab fragment of anti-hiv1 gp120 v2 mab 697. Chain: l, m, n, o. Engineered: yes. Heavy chain of fab fragment of anti-hiv1 gp120 v2 mab 697. Chain: h, i, j, k. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek-293. Expression_system_cell_line: hek-293
Resolution:
2.49Å     R-factor:   0.180     R-free:   0.238
Authors: R.M.Pan,X.P.Kong
Key ref: M.K.Gorny et al. (2012). Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals. Virology, 427, 198-207. PubMed id: 22402248
Date:
11-Jan-12     Release date:   21-Mar-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q6GMX4  (Q6GMX4_HUMAN) -  IGL@ protein from Homo sapiens
Seq:
Struc: 		236 a.a.
214 a.a.*
Protein chains
Pfam   ArchSchema ?
Q6GMX6  (Q6GMX6_HUMAN) -  IGH@ protein from Homo sapiens
Seq:
Struc: 		465 a.a.
222 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 69 residue positions (black crosses)

 

 
Virology 427:198-207 (2012)
PubMed id: 22402248  
 
 
Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals.
M.K.Gorny, R.Pan, C.Williams, X.H.Wang, B.Volsky, T.O'Neal, B.Spurrier, J.M.Sampson, L.Li, M.S.Seaman, X.P.Kong, S.Zolla-Pazner.
 
  ABSTRACT  
 
No abstract given.

 

 

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