UniProt functional annotation for P12385

UniProt code: P12385.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. {ECO:0000250, ECO:0000269|PubMed:7556078}.
 
Subunit: Heterodimer of two subunits, one of which binds GTP. Interacts with TPA1. {ECO:0000269|PubMed:16809762}.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Ptm: N5-methylated on Gln-182 by MTQ2. {ECO:0000269|PubMed:15509572, ECO:0000269|PubMed:16321977}.
Miscellaneous: Present with 13100 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity: Belongs to the eukaryotic release factor 1 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.