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UniProt functional annotation for Q12377 | ||
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| UniProt code: Q12377. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, RPN6 is required for proteasome assembly. {ECO:0000269|PubMed:12486135, ECO:0000269|PubMed:15611133, ECO:0000269|PubMed:9426256}. |
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| Subunit: | |
Component of the lid subcomplex of the 19S proteasome regulatory particle complex (also named PA700 complex). The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. {ECO:0000269|PubMed:12486135, ECO:0000269|PubMed:15611133}. |
| Ptm: | |
N-acetylated by NAT1. {ECO:0000269|PubMed:12504901}. |
| Miscellaneous: | |
Present with 16800 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the proteasome subunit S9 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.