UniProt functional annotation for Q01939

UniProt code: Q01939.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). {ECO:0000250, ECO:0000269|PubMed:25042801}.
 
Subunit: May form a homodimer or a heterodimer with a related family member. Interacts with OLA1, TMA17, and UBR1. {ECO:0000269|PubMed:10688918, ECO:0000269|PubMed:16284124, ECO:0000269|PubMed:25042801}.
Subcellular location: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
Ptm: N-acetylated by NAT1. {ECO:0000269|PubMed:12504901}.
Miscellaneous: Present with 4700 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity: Belongs to the AAA ATPase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.