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UniProt functional annotation for P33299 | ||
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| UniProt code: P33299. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). {ECO:0000250}. |
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| Subunit: | |
Interacts with UBR1 and CIC1. {ECO:0000269|PubMed:10688918, ECO:0000269|PubMed:11500370}. |
| Subcellular location: | |
Cytoplasm {ECO:0000305}. Nucleus {ECO:0000269|PubMed:14562095}. |
| Ptm: | |
The N-terminus is blocked. |
| Miscellaneous: | |
Present with 105 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the AAA ATPase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.