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UniProt functional annotation for Q9H6T3 | ||
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| UniProt code: Q9H6T3. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. {ECO:0000269|PubMed:17643375}. |
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| Subunit: | |
Tightly associated with the RNA polymerase II complex (PubMed:17643375). Component of the R2TP complex composed at least of PIHD1, RUVBL1, RUVBL2 and RPAP3 (PubMed:20864032). Interacts with PIH1D1 (PubMed:21078300). Interacts with TSC1 and TSC2 (PubMed:28561026). Interacts with PRPF8 and EFTUD2 in a ZNHIT2- dependent manner (PubMed:28561026). {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:20864032, ECO:0000269|PubMed:21078300, ECO:0000269|PubMed:28561026}. |
| Similarity: | |
Belongs to the RPAP3 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.