PDBsum entry 4c49

Transport protein

PDB id: 4c49

Contents

Protein chains

367 a.a.

Ligands

HCY ×4

Waters ×38

PDB id:

4c49

Name:

Transport protein

Title:

Reactive loop cleaved human cbg in complex with cortisol

Structure:

Corticosteroid-binding globulin. Chain: a, b, c, d. Fragment: residues 33-405. Synonym: cbg, serpin a6, transcortin. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Tissue: blood plasma. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.

Resolution:

2.70Å R-factor: 0.223 R-free: 0.268

Authors:

W.L.Chan,A.Zhou,R.J.Read

Key ref:

W.L.Chan et al. Role of sa-Hd loop movement in cortisol release mecha of cbg. To be published, .

Date:

02-Sep-13 Release date: 01-Oct-14

Protein chains

P08185  (CBG_HUMAN) -  Corticosteroid-binding globulin from Homo sapiens

Seq: 405 a.a.

Struc: 367 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)