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UniProt functional annotation for P36106 | ||
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| UniProt code: P36106. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Negative regulator of transcription elongation. {ECO:0000269|PubMed:14704159}. |
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| Subunit: | |
Interacts with the RNA polymerase RPB1 subunit and specifically with the trimethylated H3 histone H3K4me3. {ECO:0000269|PubMed:14704159, ECO:0000269|PubMed:17142463}. |
| Subcellular location: | |
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00651}. |
| Domain: | |
The PHD domain is involved in the binding to H3K4me3. {ECO:0000269|PubMed:14704159, ECO:0000269|PubMed:17142463}. |
| Miscellaneous: | |
Present with 892 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the BYE1 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.