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UniProt functional annotation for Q08981 | ||
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| UniProt code: Q08981. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Negative regulator of GDH1, the activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C), and which is required for exit from mitosis, cytokinesis and formation of prereplicative complexes in G1. {ECO:0000269|PubMed:17030612}. |
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| Subunit: | |
Interacts with CDH1, BMH1 and BMH2. {ECO:0000269|PubMed:17030612}. |
| Induction: | |
Expressed very quickly after G1 release, just prior to initiation of DNA replication. {ECO:0000269|PubMed:17030612}. |
| Miscellaneous: | |
Present with 688 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
Annotations taken from UniProtKB at the EBI.