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PDBsum entry 4avx

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protein ligands metals links
Signaling protein PDB id
4avx

 

 

 

 

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Contents
Protein chain
218 a.a.
Ligands
EDO ×8
ITP
Metals
_ZN ×2
Waters ×148
PDB id:
4avx
Name: Signaling protein
Title: Hepatocyte growth factor-regulated tyrosine kinase substrate (hgs-hrs) bound to an ip2 compound at 1.68 a resolution
Structure: Hepatocyte growth factor-regulated tyrosine kinase substrate. Chain: a. Fragment: vhs and fyve domains, residues 691-915. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
1.68Å     R-factor:   0.184     R-free:   0.231
Authors: E.Williams,P.Canning,L.Shrestha,T.Krojer,M.Vollmar,A.Slowey,S.Conway, F.Von Delft,C.H.Arrowsmith,A.M.Edwards,J.Weigelt,C.Bountra,A.Bullock
Key ref: E.Williams et al. Crystal structure of the tandem vhs and fyve domains hepatocyte growth factor-Regulated tyrosine kinase substrate (hgs-Hrs) bound to an ip2 compound at 1.68 resolution. To be published, .
Date:
30-May-12     Release date:   13-Jun-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
O14964  (HGS_HUMAN) -  Hepatocyte growth factor-regulated tyrosine kinase substrate from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
777 a.a.
218 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

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