PDBsum entry 4atz

Viral protein/de novo protein

PDB id: 4atz

Contents

Protein chains

182 a.a.

171 a.a.

154 a.a.

Waters ×735

PDB id:

4atz

Name:

Viral protein/de novo protein

Title:

Ad5 knob in complex with a designed ankyrin repeat protein

Structure:

Fiber protein. Chain: a, b, c. Synonym: spike,protein iv. Engineered: yes. Designed ankyrin repeat protein. Chain: d, e, f

Source:

Human adenovirus c serotype 5. Hadv-5. Organism_taxid: 28285. Gene: l5. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630

Resolution:

1.95Å R-factor: 0.163 R-free: 0.193

Authors:

P.R.E.Mittl,C.Hess,B.Dreier

Key ref:

B.Dreier et al. (2013). Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters. Proc Natl Acad Sci U S A, 110, E869. PubMed id: 23431166 DOI: 10.1073/pnas.1213653110

Date:

11-May-12 Release date: 27-Feb-13

Protein chains

P11818  (SPIKE_ADE05) -  Fiber protein from Human adenovirus C serotype 5

Seq: 581 a.a.

Struc: 182 a.a.

Protein chain

P11818  (SPIKE_ADE05) -  Fiber protein from Human adenovirus C serotype 5

Seq: 581 a.a.

Struc: 171 a.a.

Protein chains

No UniProt id for this chain

Struc: 154 a.a.

DOI no: 10.1073/pnas.1213653110

Proc Natl Acad Sci U S A 110:E869 (2013)

PubMed id: 23431166

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.

B.Dreier, A.Honegger, C.Hess, G.Nagy-Davidescu, P.R.Mittl, M.G.Grütter, N.Belousova, G.Mikheeva, V.Krasnykh, A.Plückthun.

ABSTRACT

No abstract given.