PDBsum entry 4apq

Immune system

PDB id: 4apq

Contents

Protein chains

290 a.a.

99 a.a.

196 a.a.

240 a.a.

Ligands

NAG-NAG

NAG-NAG-BMA-MAN

NAG-NAG-BMA

CIS

Waters ×2

PDB id:

4apq

Name:

Immune system

Title:

Crystal structure of autoreactive-valpha14-vbeta6 nkt tcr in complex with cd1d-sulfatide

Structure:

Antigen-presenting glycoprotein cd1d1. Chain: a. Fragment: extracellular domain, residues 19-297. Synonym: cd1d.1, cd1d. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes. Mouse nkt tcr valpha14, human nkt tcr valpha14.

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: ril.

Resolution:

3.00Å R-factor: 0.180 R-free: 0.232

Authors:

A.J.Clarke,J.Le Nours,J.Rossjohn

Key ref:

O.Patel et al. Type-Ii natural killer t cell antigen receptor mediat recognition of cd1d-Sulfatide. To be published, .

Date:

05-Apr-12 Release date: 24-Apr-13

Protein chain

P11609  (CD1D1_MOUSE) -  Antigen-presenting glycoprotein CD1d1 from Mus musculus

Seq: 336 a.a.

Struc: 290 a.a.*

Protein chain

P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus

Seq: 119 a.a.

Struc: 99 a.a.

Protein chain

P01848  (TCA_HUMAN) -  T cell receptor alpha chain constant from Homo sapiens

Seq: 140 a.a.

Struc: 196 a.a.*

Protein chain

No UniProt id for this chain

Struc: 240 a.a.

* PDB and UniProt seqs differ at 18 residue positions (black crosses)