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UniProt functional annotation for P78972 | ||
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| UniProt code: P78972. |
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| Organism: | |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. |
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| Function: | |
Required for mad2-dependent spindle checkpoint activation. Promotes ubiquitin-dependent degradation of cdc13 by the anaphase promoting complex/cyclosome (APC/C). {ECO:0000269|PubMed:15791259, ECO:0000269|PubMed:9001228, ECO:0000269|PubMed:9461438}. |
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| Subunit: | |
Interacts with cdc13, mad3 and mes1. {ECO:0000269|PubMed:11909965, ECO:0000269|PubMed:15791259}. |
| Similarity: | |
Belongs to the WD repeat CDC20/Fizzy family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.