PDBsum entry 4adx

Ribosome

PDB id: 4adx

Contents

Protein chains

56 a.a.*

46 a.a.*

92 a.a.*

90 a.a.*

50 a.a.*

96 a.a.*

77 a.a.*

237 a.a.*

337 a.a.*

246 a.a.*

139 a.a.*

172 a.a.*

119 a.a.*

78 a.a.*

156 a.a.*

220 a.a.*

139 a.a.*

132 a.a.*

140 a.a.*

182 a.a.*

185 a.a.*

115 a.a.*

142 a.a.*

95 a.a.*

150 a.a.*

81 a.a.*

117 a.a.*

52 a.a.*

64 a.a.*

154 a.a.*

82 a.a.*

108 a.a.*

73 a.a.*

DNA/RNA

* C-alpha coords only

PDB id:

4adx

Name:

Ribosome

Title:

The cryo-em structure of the archaeal 50s ribosomal subunit in complex with initiation factor 6

Structure:

23s ribosomal RNA. Chain: 0. Rpl37e. Chain: 1. Rpl39e. Chain: 2. Rpl44e. Chain: 3. Rpl34e.

Source:

Methanothermobacter thermautotrophicus. Organism_taxid: 187420. Strain: delta h. Cellular_location: cytoplasm. Cellular_location: cytoplasm

Authors:

B.J.Greber,D.Boehringer,V.Godinic-Mikulcic,A.Crnkovic,M.Ibba, I.Weygand-Durasevic,N.Ban

Key ref:

B.J.Greber et al. (2012). Cryo-EM structure of the archaeal 50S ribosomal subunit in complex with initiation factor 6 and implications for ribosome evolution. J Mol Biol, 418, 145-160. PubMed id: 22306461

Date:

04-Jan-12 Release date: 08-Feb-12

Protein chain

P32410  (RL37_HALMA) -  Large ribosomal subunit protein eL37 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 57 a.a.

Struc: 56 a.a.

Protein chain

P22452  (RL39_HALMA) -  Large ribosomal subunit protein eL39 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 50 a.a.

Struc: 46 a.a.

Protein chain

P32411  (RL44E_HALMA) -  Large ribosomal subunit protein eL42 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 92 a.a.

Struc: 92 a.a.

Protein chain

P0DJ23  (RL34_TETTS) -  Large ribosomal subunit protein eL34 from Tetrahymena thermophila (strain SB210)

Seq: 123 a.a.

Struc: 90 a.a.

Protein chain

P0DJ25  (RL40_TETTS) -  Ubiquitin-ribosomal protein eL40 fusion protein from Tetrahymena thermophila (strain SB210)

Seq: 129 a.a.

Struc: 50 a.a.

Protein chain

P0DJ59  (RL30_TETTS) -  Large ribosomal subunit protein eL30 from Tetrahymena thermophila (strain SB210)

Seq: 104 a.a.

Struc: 96 a.a.

Protein chain

Q24C27  (RL14_TETTS) -  Large ribosomal subunit protein eL14 from Tetrahymena thermophila (strain SB210)

Seq: 126 a.a.

Struc: 77 a.a.

Protein chain

P20276  (RL2_HALMA) -  Large ribosomal subunit protein uL2 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 240 a.a.

Struc: 237 a.a.

Protein chain

P20279  (RL3_HALMA) -  Large ribosomal subunit protein uL3 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 338 a.a.

Struc: 337 a.a.

Protein chain

P12735  (RL4_HALMA) -  Large ribosomal subunit protein uL4 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 246 a.a.

Struc: 246 a.a.

Protein chain

P14124  (RL5_HALMA) -  Large ribosomal subunit protein uL5 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 177 a.a.

Struc: 139 a.a.

Protein chain

P14135  (RL6_HALMA) -  Large ribosomal subunit protein uL6 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 178 a.a.

Struc: 172 a.a.

Protein chain

P12743  (RL7A_HALMA) -  Large ribosomal subunit protein eL8 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 120 a.a.

Struc: 119 a.a.

Protein chain

O27647  (RL18A_METTH) -  Large ribosomal subunit protein eL20 from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

Seq: 78 a.a.

Struc: 78 a.a.

Protein chain

P60617  (RL10E_HALMA) -  Large ribosomal subunit protein uL16 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 177 a.a.

Struc: 156 a.a.

Protein chain

O27648  (IF6_METTH) -  Translation initiation factor 6 from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

Seq: 222 a.a.

Struc: 220 a.a.

Protein chain

No UniProt id for this chain

Struc: 139 a.a.

Protein chain

P22450  (RL14_HALMA) -  Large ribosomal subunit protein uL14 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 132 a.a.

Struc: 132 a.a.

Protein chain

P12737  (RL15_HALMA) -  Large ribosomal subunit protein uL15 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 165 a.a.

Struc: 140 a.a.

Protein chain

P60618  (RL15E_HALMA) -  Large ribosomal subunit protein eL15 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 196 a.a.

Struc: 182 a.a.

Protein chain

P14123  (RL18_HALMA) -  Large ribosomal subunit protein uL18 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 187 a.a.

Struc: 185 a.a.

Protein chain

P12733  (RL18E_HALMA) -  Large ribosomal subunit protein eL18 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 116 a.a.

Struc: 115 a.a.

Protein chain

P14119  (RL19E_HALMA) -  Large ribosomal subunit protein eL19 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 149 a.a.

Struc: 142 a.a.

Protein chain

P12734  (RL21_HALMA) -  Large ribosomal subunit protein eL21 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 96 a.a.

Struc: 95 a.a.

Protein chain

P10970  (RL22_HALMA) -  Large ribosomal subunit protein uL22 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 155 a.a.

Struc: 150 a.a.

Protein chain

P12732  (RL23_HALMA) -  Large ribosomal subunit protein uL23 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 85 a.a.

Struc: 81 a.a.

Protein chain

P10972  (RL24_HALMA) -  Large ribosomal subunit protein uL24 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 120 a.a.

Struc: 117 a.a.

Protein chain

P14116  (RL24E_HALMA) -  Large ribosomal subunit protein eL24 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 67 a.a.

Struc: 52 a.a.

Protein chain

P10971  (RL29_HALMA) -  Large ribosomal subunit protein uL29 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 71 a.a.

Struc: 64 a.a.

Protein chain

P14121  (RL30_HALMA) -  Large ribosomal subunit protein uL30 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 154 a.a.

Struc: 154 a.a.

Protein chain

P18138  (RL31_HALMA) -  Large ribosomal subunit protein eL31 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 92 a.a.

Struc: 82 a.a.

Protein chain

P12736  (RL32_HALMA) -  Large ribosomal subunit protein eL32 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 241 a.a.

Struc: 108 a.a.

Protein chain

P60619  (RL37A_HALMA) -  Large ribosomal subunit protein eL43 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)

Seq: 92 a.a.

Struc: 73 a.a.

DNA/RNA chains

A-U-G-C-C-A-G-C-U-G-G-U-G-G-A-U-U-G-C-U-C-G-G-C-U-C-A-G-G-C-G-C-U-G-A-U-G-A-A- ... 2688 bases

G-U-G-G-A-G-G-U-G-U-A-A-A-A-A-C-C-U-U-C-G-A-A-G-U-G-G-U-C-A-A-C-A-C-A-A-C-A-G- 133 bases

U-A-G-G-C-G-G-C-C-A-C-A-G-C-G-G-U-G-G-G-G-U-U-G-C-C-U-C-C-C-G-U-A-C-C-C-A-U-C- 121 bases

Enzyme reactions

• Enzyme class: Chains 1, 2, 3, 4, 5, 6, 7, A, B, C, D, E, F, G, H, I, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z: E.C.?

J Mol Biol 418:145-160 (2012)

PubMed id: 22306461

Cryo-EM structure of the archaeal 50S ribosomal subunit in complex with initiation factor 6 and implications for ribosome evolution.

B.J.Greber, D.Boehringer, V.Godinic-Mikulcic, A.Crnkovic, M.Ibba, I.Weygand-Durasevic, N.Ban.

ABSTRACT

No abstract given.