PDBsum entry 4a4z

Hydrolase

PDB id: 4a4z

Contents

Protein chain

874 a.a.

Ligands

ANP

EDO ×4

Waters ×133

PDB id:

4a4z

Name:

Hydrolase

Title:

Crystal structure of the s. Cerevisiae dexh helicase ski2 bound to amppnp

Structure:

Antiviral helicase ski2. Chain: a. Fragment: residues 296-1287. Synonym: ski2, superkiller protein 2. Engineered: yes

Source:

Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five.

Resolution:

2.40Å R-factor: 0.240 R-free: 0.275

Authors:

F.Halbach,M.Rode,E.Conti

Key ref:

F.Halbach et al. (2012). The crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosome. Rna, 18, 124-134. PubMed id: 22114319

Date:

20-Oct-11 Release date: 21-Dec-11

Protein chain

P35207  (SKI2_YEAST) -  Antiviral helicase SKI2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Seq: 1287 a.a.

Struc: 874 a.a.

Enzyme reactions

• Enzyme class: E.C.3.6.4.13 - Rna helicase.
• Reaction: ATP + H2O = ADP + phosphate + H⁺

ATP + H2O = ADP (Bound ligand (Het Group name = ANP) matches with 81.25% similarity) + phosphate + H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Rna 18:124-134 (2012)

PubMed id: 22114319

The crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosome.

F.Halbach, M.Rode, E.Conti.

ABSTRACT

No abstract given.