PDBsum entry 4a11

DNA binding protein

PDB id: 4a11

Contents

Protein chains

1091 a.a.

365 a.a.

PDB id:

4a11

Name:

DNA binding protein

Title:

Structure of the hsddb1-hscsa complex

Structure:

DNA damage-binding protein 1. Chain: a. Synonym: ddb p127 subunit, DNA damage-binding protein a, ddba, damage-specific DNA-binding protein 1, hbv x-associated protein 1, xap-1, uv-damaged DNA-binding factor, uv-damaged DNA-binding protein 1, uv-ddb 1, xpe-binding factor, xpe-bf, xeroderma pigmentosum group e-complementing protein, xpce, cockayne syndrome a protein. Engineered: yes. DNA excision repair protein ercc-8.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichopulsia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five.

Resolution:

3.31Å R-factor: 0.179 R-free: 0.233

Authors:

K.Bohm,A.Scrima,E.S.Fischer,H.Gut,N.H.Thomae

Key ref:

E.S.Fischer et al. (2011). The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation. Cell, 147, 1024-1039. PubMed id: 22118460

Date:

13-Sep-11 Release date: 07-Dec-11

Protein chain

Q16531  (DDB1_HUMAN) -  DNA damage-binding protein 1 from Homo sapiens

Seq: 1140 a.a.

Struc: 1091 a.a.

Protein chain

Q13216  (ERCC8_HUMAN) -  DNA excision repair protein ERCC-8 from Homo sapiens

Seq: 396 a.a.

Struc: 365 a.a.

Cell 147:1024-1039 (2011)

PubMed id: 22118460

The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.

E.S.Fischer, A.Scrima, K.Böhm, S.Matsumoto, G.M.Lingaraju, M.Faty, T.Yasuda, S.Cavadini, M.Wakasugi, F.Hanaoka, S.Iwai, H.Gut, K.Sugasawa, N.H.Thomä.

ABSTRACT

No abstract given.