PDBsum entry 4hwx

Hydrolase inhibitor

PDB id: 4hwx

Contents

Protein chain

114 a.a.

Ligands

GOL

ACT ×3

Waters ×126

PDB id:

4hwx

Name:

Hydrolase inhibitor

Title:

Crystal structure of streptomyces caespitosus sermetstatin

Structure:

Neutral proteinase inhibitor scnpi. Chain: a. Synonym: sermetstatin. Engineered: yes

Source:

Streptomyces caespitosus. Organism_taxid: 53502. Gene: scnpi. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.90Å R-factor: 0.188 R-free: 0.214

Authors:

S.Trillo-Muyo,S.Martinez-Rodriguez,J.L.Arolas,F.X.Gomis-Ruth

Key ref:

S.Trillo-Muyo et al. Mechanism of action of a janus-Faced single-Domain pr inhibitor simultaneously targeting two peptidase clas. To be published, .

Date:

09-Nov-12 Release date: 05-Dec-12

Protein chain

Q9FDS0  (Q9FDS0_STRCS) -  Neutral proteinase inhibitor ScNPI from Streptomyces caespitosus

Seq: 141 a.a.

Struc: 114 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)