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PDBsum entry 4g5s

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protein ligands Protein-protein interface(s) links
Cell cycle/signaling protein PDB id
4g5s
Jmol
Contents
Protein chains
317 a.a.
22 a.a.
21 a.a.
19 a.a.
Ligands
GDP ×3
CIT ×2
PDB id:
4g5s
Name: Cell cycle/signaling protein
Title: Structure of lgn gl3/galphai3 complex
Structure: Guanine nucleotide-binding protein g(k) subunit a chain: a, b, c, d. Fragment: unp residues 25-354. Synonym: g(i) alpha-3. Engineered: yes. G-protein-signaling modulator 2. Chain: e, g, z, f. Fragment: goloco 3 (unp residues 594-618). Synonym: pins homolog.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gnai3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Mus musculus. Mouse.
Resolution:
3.62Å     R-factor:   0.210     R-free:   0.253
Authors: M.Jia,J.Li,J.Zhu,W.Wen,M.Zhang,W.Wang
Key ref: M.Jia et al. Crystal structures of the scaffolding protein lgn rev general mechanism by which goloco binding motifs inhi release of gdp from galphai subunits in g-Coupled heterotrimeric proteins. To be published, .
Date:
18-Jul-12     Release date:   05-Sep-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P08754  (GNAI3_HUMAN) -  Guanine nucleotide-binding protein G(k) subunit alpha
Seq:
Struc:
354 a.a.
317 a.a.
Protein chains
Pfam   ArchSchema ?
Q8VDU0  (GPSM2_MOUSE) -  G-protein-signaling modulator 2
Seq:
Struc:
 
Seq:
Struc:
679 a.a.
22 a.a.
Protein chain
Pfam   ArchSchema ?
Q8VDU0  (GPSM2_MOUSE) -  G-protein-signaling modulator 2
Seq:
Struc:
 
Seq:
Struc:
679 a.a.
21 a.a.
Protein chain
Pfam   ArchSchema ?
Q8VDU0  (GPSM2_MOUSE) -  G-protein-signaling modulator 2
Seq:
Struc:
 
Seq:
Struc:
679 a.a.
19 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   13 terms 
  Biological process     cell cycle   13 terms 
  Biochemical function     nucleotide binding     11 terms