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PDBsum entry 4dy0
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Hydrolase inhibitor
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PDB id
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4dy0
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PDB id:
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| Name: |
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Hydrolase inhibitor
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Title:
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Crystal structure of native protease nexin-1 with heparin
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Structure:
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Glia-derived nexin. Chain: a, b. Synonym: gdn, peptidase inhibitor 7, pi-7, protease nexin 1, pn-1, protease nexin i, serpin e2. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: serpine2, pi7, pn1. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.35Å
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R-factor:
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0.184
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R-free:
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0.226
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Authors:
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J.A.Huntington,W.Li
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Key ref:
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W.Li
and
J.A.Huntington
(2012).
Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism.
Blood,
120,
459-467.
PubMed id:
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Date:
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28-Feb-12
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Release date:
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15-Aug-12
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PROCHECK
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Headers
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References
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P07093
(GDN_HUMAN) -
Glia-derived nexin from Homo sapiens
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Seq:
Struc:
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398 a.a.
362 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Blood
120:459-467
(2012)
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PubMed id:
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Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism.
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W.Li,
J.A.Huntington.
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ABSTRACT
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Links
