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PDBsum entry 3zzw
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PDB id:
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Transferase
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Title:
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Crystal structure of the kinase domain of ror2
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Structure:
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Tyrosine-protein kinase transmembrane receptor ror2. Chain: a, b. Fragment: kinase domain, residues 463-751. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Other_details: mammalian gene collection, open biosystems (mgc)
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Resolution:
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2.90Å
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R-factor:
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0.190
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R-free:
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0.247
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Authors:
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L.Tresaugues,M.Moche,C.H.Arrowsmith,H.Berglund,C.Bountra,A.M.Edwards, T.Ekblad,S.Graslund,T.Karlberg,T.Nyman,H.Schuler,A.G.Thorsell, J.Weigelt,P.Nordlund,Structural Genomics Consortium (Sgc)
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Key ref:
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L.Tresaugues
et al.
Crystal structure of the kinase domain of ror2.
To be published,
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Date:
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05-Sep-11
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Release date:
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14-Sep-11
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PROCHECK
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Headers
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References
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Q01974
(ROR2_HUMAN) -
Tyrosine-protein kinase transmembrane receptor ROR2 from Homo sapiens
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Seq:
Struc:
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943 a.a.
269 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.10.1
- receptor protein-tyrosine kinase.
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Reaction:
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L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
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L-tyrosyl-[protein]
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+
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ATP
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=
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O-phospho-L-tyrosyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
