PDBsum entry 3zqk

Blood clotting

PDB id: 3zqk

Contents

Protein chain

181 a.a.

Ligands

GOL ×2

NAG ×6

Metals

_CA ×3

Waters ×508

PDB id:

3zqk

Name:

Blood clotting

Title:

Von willebrand factor a2 domain with calcium

Structure:

Von willebrand factor. Chain: a, b, c. Fragment: a2 domain, residues 1478-1674. Synonym: vwf, von willebrand antigen 2, von willebrand antigen ii. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293-ebna1-s

Resolution:

1.70Å R-factor: 0.157 R-free: 0.200

Authors:

A.J.Jakobi,E.G.Huizinga

Key ref:

A.J.Jakobi et al. (2011). Calcium modulates force sensing by the von Willebrand factor A2 domain. Nat Commun, 2, 385. PubMed id: 21750539

Date:

09-Jun-11 Release date: 27-Jul-11

Protein chains

P04275  (VWF_HUMAN) -  von Willebrand factor from Homo sapiens

Seq: 2813 a.a.

Struc: 181 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Nat Commun 2:385 (2011)

PubMed id: 21750539

Calcium modulates force sensing by the von Willebrand factor A2 domain.

A.J.Jakobi, A.Mashaghi, S.J.Tans, E.G.Huizinga.

ABSTRACT

No abstract given.